Clinico-epidemiological study of Vitiligo in Egyptian Children

Document Type : Original Article

Authors

1 Professor of Dermatology, Venereology and Andrology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

2 Assistant Professor of Dermatology, Venereology and Andrology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

3 Professor of Clinical pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

4 MBBCh, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

https://doi.org/10.21608/aimj.2025.446664

Abstract

Background: Depigmented patches of skin are the hallmark of vitiligo. It impacts all racial groups equally and affects between 0.1 and 2% of the global population, including both adults and children of both sexes. Positive family history is present in about 30–40% of patients.
Aim and objectives: To evaluate anthropometric measurements, serum levels of zinc and copper in Egyptian children with vitiligo and their relation to the severity of the disease.
Subjects and methods: From May 2024 to March 2025, researchers at the Dermatology Department, Faculty of Medicine, Al-Azhar University recruited 100 vitiligo patients and 70 healthy individuals who were age and sex matched.
Results: As regard comparison of Zn level between studied groups, the median Zn was 98.5 with IQR of 78.5-141.7 while in Control group, median Zn was 107.5 with IQR of 88-143 but difference was insignificant. As regard comparison of Cu level between studied groups. In patient's group, median Cu was 104.5 with IQR of 74-139.7 while in Control group, median Cu was 115.5 with IQR of 82-139, but difference was insignificant.
Conclusion: Despite low Zn and Cu serum levels in case group in comparison with control group, it was insignificant in children with vitiligo, there is no significant difference regarding anthropometric measures in the studied group.
 

Keywords