Early doppler ultrasound screening in prediction of hypertensive disorders of pregnancy

Document Type : Original Article

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Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Assuit, Egypt

https://doi.org/10.21608/aimj.2025.446637

Abstract

Background: Preeclampsia is a pregnancy-specific hypertensive illness that continues to impact the practice of obstetrics globally despite several advances in antenatal care.
Aim: To detect the uterine artery Doppler value in two intervals, 11-13 weeks and 22-24 weeks, in the early prediction of hypertensive illnesses of pregnancy.
Patients and methods: This prospective research has been carried out on 100 pregnant females attending routine antenatal care visits at the outpatient clinics of Obstetrics and Gynecology in Luxor International Medical Complex and Al-Azhar University Hospitals, aiming to evaluate and analyze their health outcomes and experiences.
Results: At 11–13 weeks (UAD1), the cutoff value for Right Uterine Artery PI was 1.43, with an AUC of 0.9973, showing 100% sensitivity and 88% specificity (P < 0.0001*). For Left Uterine Artery PI, the cutoff was 1.45, with an area under the curve of 0.9973, 100% sensitivity, and 90.2% specificity (P < 0.0001*). At 22–24 weeks (UAD2), the cutoff for Right Uterine Artery PI was 0.735, with an area under the curve of 0.998, 100% sensitivity, and 85.9% specificity (P < 0.0001*). For Left Uterine Artery PI, the cutoff was 0.81, with a perfect area under the curve of 1, 100% sensitivity, and 96.7% specificity (P < 0.0001*). These results highlight the strong predictive accuracy of uterine artery PI in identifying hypertensive disorders during pregnancy.
Conclusion: The uterine artery Doppler is a valuable tool for predicting Preeclampsia and other pregnancy-related hypertension disorders, but further research is needed with a larger sample size.
 

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