Early Outcome after Aortic Valve Replacement with a Sutureless Bioprosthesis

Sallam, Ahmed Hussein Mostafa; Gamil, El Husseiny El Husseiny; Salem, Al Sayed Mahmoud Mohammed; Abu- Elhasan, Hatem Mohammed Abu-El Azayem Mohammed

doi:10.21608/aimj.2025.446611

Early Outcome after Aortic Valve Replacement with a Sutureless Bioprosthesis

Document Type : Original Article

Authors

¹ Fellow of Congenital Cardiac Surgery, Birmingham Children’s hospital, Birmingham, UK

² Cardiothoracic Surgery, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt

³ Pediatrics Cardiac Surgery, National Heart Institute, Cairo, Egypt

10.21608/aimj.2025.446611

Abstract

Background: Aortic stenosis is one of the most prevalent valvular disorders. In people experiencing symptoms, the life expectancy decreases if the condition is not addressed. The only effective treatment for significant aortic lesions is valve replacement. This study aimed at reporting the early clinical outcomes of aortic valve replacement with Perceval sutureless bioprosthesis.
Methods: The study involved 50 patients aged 21 to 82 years, comprising both genders, who were indicated for aortic valve replacement with or without additional cardiac procedures and consented to participate. Patients were included based on their desire for or indication of receiving a tissue valve.
Results: Dedicated Aortic cross clamp time was 43.90±7.53 minutes, and Effective orifice Area at discharge was 1.51±0.12. Hemodynamics assessment at discharge showed good function of all implanted valves with low trans-valvular pressure gradients (mean, 11.14±4.19 mmHg and peak, 20.72±7.31mm Hg) and low incidence of paravalvular leakage. We had one In-hospital mortality (2%). Up to six months after surgery, survivors demonstrated a positive clinical outcome, and the valve prosthesis maintained stable hemodynamic functionality. One patient (2%) had a Paravalvular leak progressing over time and required reoperation. Permanent pacemaker incidence was 6%.
Conclusions: Prosthetic hemodynamic performance was satisfactory, early results showed a high rate of successful implantation, and times for aortic cross-clamp and cardiopulmonary bypass were shorter than those for traditional aortic valve replacement, according to published data. Mortality and morbidity rates were also low.

Keywords