Document Type : Original Article
Authors
1
Professor of Dermatology, Venereology and Andrology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
2
Assistant Professor of Dermatology, Venereology and Andrology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
3
MBBCh, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
https://doi.org/10.21608/aimj.2025.446570
Abstract
Background: One of the most prevalent chronic inflammatory skin disorders, psoriasis is increasingly thought of as a systemic disease as well as a skin condition. Epidermal hyperproliferation, aberrant keratinocyte differentiation, angiogenesis accompanied by dilated blood vessels, and an overabundance of Th-1 cells are the hallmarks of this condition.
Aim and objectives: The goals of this study are(1) to compare adult psoriasis vulgaris patients with healthy controls of the same age and sex and (2) to identify the frequency of metabolic syndrome in this population and, if present, to connect this condition with the severity of psoriasis.
Subjects and methods: One hundred adults suffering from psoriasis vulgaris (the "psoriatic group") and seventy healthy controls (the "healthy group") were studied in a cross-sectional fashion between 2021 and 2024 in the Dermatology Department of El-Hussein University Hospital, Faculty of Medicine Al-Azhar University. The samples were taken at random.
Results: The psoriatic group had a higher prevalence of metabolic syndrome (20% vs. 14.29%, p = 0.33) than the healthy group. In comparison to the control group, psoriasis patients had higher averages for height, weight, and body mass index (BMI). The psoriatic group exhibited higher mean serum triglyceride and cholesterol levels but significantly lower random blood sugar levels than the healthy group.
Conclusion: Lastly, the study's findings lend credence to the notion that metabolic syndrome and psoriasis are connected, particularly in the most severe cases of the condition.
Keywords
)
View on SCiNiTO