Clinicoepidemiological study of hepatocellular carcinoma cases attend in AL-AZHAR University hospitals

Dorrah, Ahmed Osama Mohamed; Gomaa, Walid Mohamed Mousa; Mahmoud, Abd El Sattar Mohamed Abd El Ghany

doi:10.21608/aimj.2025.446425

Clinicoepidemiological study of hepatocellular carcinoma cases attend in AL-AZHAR University hospitals

Document Type : Original Article

Authors

Hepatogastroenterology and Infectious Disease, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt

10.21608/aimj.2025.446425

Abstract

Background: Hepatocellular carcinoma (HCC), which is responsible for over eighty percent of liver cancers, is one of the top three reasons for cancer-correlated deaths in forty-six nations.
Aim: Epidemiological and clinical study of HCC attend in Al-Azhar University hospitals.
Patients and methods: This cross-sectional study was conducted at the Hepatogastroenterology and Infectious Disease Department in Al-Azhar University hospitals and lasted for 12 months. It was conducted on 100 patients.
Results: Regarding clinical manifestations of HCC patients, 88% have ascites, 82% have weight loss, 79% have abdominal pain, 67% have jaundice, 66% have varices, 56% have lower limb edema, and 21% developed hepatic encephalopathy. Among the 82 patients who had ascites, 31.7% had mild ascites, 63.4% had moderate ascites, and 4.9% had severe ascites. Among patients with HCC, the Child score ranged between 5 and 14, with a mean value of 8.84±2.48. Child class was A in 24%, B in 30% and C in 46%. AlBi score ranged between -3.41 to -1.30 with mean value of -2.46±0.52.AlBi grade I was detected in 41%, grade II in 57% and grade III in 2% of HCC patients. BCLC category A was detected in 15%, category B in 22%, category C in 45% and category D in 18% of HCC.
Conclusion: The study primarily involved male, rural, non-working, married patients with HCC, liver cirrhosis, ascites, well-defined tumors, and metastasis, with a mean Child score of C.

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