Evaluation of Effect of Bariatric Surgery on Male Erectile Dysfunction

Authors

1 Professor of General Surgery, Faculty of Medicine, Al- Azhar University, Cairo, Egypt

2 Professor of Diagnostic Radiology, Faculty of Medicine, Al- Azhar University, Cairo, Egypt

3 Professor of Clinical Pathology , Faculty of Medicine, Al- Azhar University, Cairo, Egypt

4 Assistant Professor of General Surgery, Faculty of Medicine, Al- Azhar University, Cairo, Egypt

5 MSc, General Surgery

Abstract

Background: Bariatric surgery is now the most effective treatment for significant and long-term weight reduction. Weight loss may have an effect on specific metabolic and vascular pathways shared by endothelial dysfunction and erectile dysfunction. Aim of the work: To evaluate how surgically induced weight loss affects obese people undergoing bariatric surgery's ability to erect a penis. Additionally, we sought to investigate the postulated underlying mechanism linked to the enhancement of erectile function following weight loss by bariatric surgery. Patients and Methods: After undergoing bariatric surgery, fifty obese men in a row were monitored for a year. Biochemical testing, including triglycerides, interleukin-6, C-reactive protein, total serum cholesterol, and endothelial nitric oxide synthase, as well as erectile function tests, were carried out on individuals prior to and after twelve months following bariatric surgery. For leaky penial doplex, scores on the International Index of Erectile Function (IIEF) were documented. Results: Before and after surgery, fifty males (mean age 39 ±14.6 years, vary 24-62; mean BMI 41.2 ±4.8 kg/m2) performed questionnaires and biochemical tests. The average weight loss was 34.8 kg and BMI dropped 8.6 kg/m2 after 12 months. IIEF scores for 65 sexually active adults, before and after surgery, significantly improved erectile function (21.2±5.7 against 26.5±4.5; P=.02). 70 males were not sexually active before surgery, but five (20.7%) started having sex. Triglyceride and cholesterol levels in the serum of men decreased significantly. The activity of nitric oxide synthase increased significantly (P

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