Value of Combination of ECG, Pulse oximetry & Blood Pressure in Screening of Congenital Heart Disease in Apparently Healthy Full Term Neonates

Authors

1 Pediatrics, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt

2 Pediatrics, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt

Abstract

Background: Every year, roughly eight out of every one thousand newborns are born with congenital heart disease (CHD), which is the most frequent form of congenital disability reported. Aim and objectives: To evaluate the validity of combining (Electrocardiogram( ECG), BL/ P, and pulse oximetry), as a screening method for the primary identifying critical CHD (CCHD) in apparent healthy full-term neonates. Patient and methods: This trial was a prospective observational study done on 100 full-term, apparent healthy neonates, and ages of gestation ranging from thirty-seven weeks to forty-two weeks from the beginning of the pregnancy were selected from deliveries at Alzahraa University Hospital Cairo, Egypt. Data were collected from May 2021 to March 2022. Results: There was a statistically significant relation between echo-abnormality and the left axis of QRS. The difference between peripheral oxygen saturation (SPO2) pre- and post-ductal showed higher values in neonates with abnormal echo than those with normal echo. The total combination of clinical examination, ECG, and SPO2 increased the sensitivity by 83.3 0%, specificity of 96.6 %, area under the curve (AUC) of 0.950 than each one alone. Conclusion: There was a high relationship between echo-abnormality and SPO2 post ductal, ECG, and clinical examination (murmur, respiratory rate, heart rate). This combination can improve the clinician's capacity to promptly recognize life-threatening congenital heart disease. Creating a national program that will prioritize screening for coronary heart disease is necessary to address this issue.

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