Study of Incidence, Risk factors and Outcomes of Ventilator Associated Pneumonia

Authors

1 Chest Diseases, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt

2 Clinical Pathology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt

3 Chest Diseases, Faculty of Medicine, El-Mergib University, Libya

Abstract

Background: Ventilator-associated pneumonia (VAP) refers to nosocomial pneumonia that occurs 48 hours or more after the initiation of mechanical ventilation (MV). Aim and objectives: To investigate the incidence, risk factors, and outcomes of ventilator-associated pneumonia (VAP) in critically ill patients receiving (MV) in the intensive care unit (ICU). Patients and methods: This prospective observational study included 50 patients who required mechanical ventilation for respiratory support in the ICU, selected from attendees of ICU units at Al-Hussein University Hospital. Results: The mortality rate associated with VAP is higher compared to those without VAP; the study has shown that VAP accounts for a significant proportion of HAP. There was a statistically significant association between the development of VAP and prolonged experience of ICU stay. Conclusion: VAP is common in critically ill patients and is possibly associated with poor outcomes (24%) of VAP patients were discharged, and (76%) of patients died. The study demonstrated that (54%) of patients had an early onset of VAP, and (46%) of the patients had a late onset of VAP. There was a significant association between the onset of VAP and the mortality rate.