Incidence, prevention and treatment of Ovarian Hypeyrstimulation Syndrome

Authors

1 Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

2 Embryology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

3 Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University, Cairo, Egypt

Abstract

Background: A systemic condition known as ovarian hyperstimulation syndrome (OHSS) develops when the ovaries release vasoactive products due to their overstimulation. Aim and Objectives: To detect the incidence, methods of prevention, & treatment of ovarian hyperstimulation syndrome at the ART unit of the International Islamic Institute of Population Studies and Research (IIIPSR) in the last three years, from 2018 until 2020. Patients and Methods: This study included 8660 patients with a high risk of ovarian hyperstimulation syndrome and was done in the ART unit of the International Islamic Institute of Population Studies & Research in the last three years, from 2018 until 2020. Results: The prevalence of OHSS in the ART unit of IIIPSR Al-Azhar University from 2018 to 2020 was 17.7%. The mild form represents 11.92% of total cases and 68% of OHSS cases; the moderate form represents 3.56% of total cases. 20% of OHSS cases, severe form represents 2% of total cases and 11.3% of OHSS cases, and patients admitted to IUC present 0.22% of total cases and 0.012% of OHSS cases. Conclusion: A key predictor for the frequency of moderate to severe OHSS, quickly rising E2 levels (E2 5,000 ng/L), and/or at least 18 follicles on trigger day is an antral follicular count (AFC) of twenty-four or higher.

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