Impact of Diabetes Mellitus in Arteriovenous Fistula Dysfunction in Patients on Regular Hemodialysis

Authors

1 Department of Internal Medicine and Nephrology, Faculty of Medicine for boys, Al-Azhar University, Cairo, Egypt

2 Department of Diagnostic and Interventional Radiology, Faculty of Medicine for boys, Al-Azhar University, Cairo, Egypt

3 M.B.B. Ch, Faculty of Medicine, Cairo University 2016

Abstract

Background: Primary arteriovenous fistula (AVF) failure has been linked to the existence of diabetes mellitus in some individuals, but not in all. Aim of the work: The study's objective is to assess how Diabetes Mellitus affects individuals receiving regular hemodialysis (HD) who have AVF malfunction. Patient and methods: All of the 90 participants in this research had end-stage renal disease (ESRD) and were being treated with regular HD. The subjects were separated into three groups according on age and sex; Group A had Twenty (20) non-diabetic patients enrolled as control group without any diagnosis of liver disease, Group B had Thirty-five (35) patients who are diabetic but are controlled where Hb A1C ≤ 7, Group C had Thirty-five (35) patients who are diabetic but are uncontrolled where Hb A1C > 7. Results: This study showed the distribution of AVF failure in the three groups, where it failed in 4(20%), 13(37.1%), and 23(65.7%) in the groups A, B, and C respectively. There was statistically substantial increase in AVF failure in groups B & C rather than group A, and in group C rather than group B. Conclusion: People with diabetes as a whole had more primary AVF failure than patients without the disease. Additionally, compared to diabetic individuals with HbA1c values