The Effect of Obstructive Sleep Apnea on Cardiovascular Profile Assessed by Ambulatory Blood Pressure and ECG MONITORING and Doppler Echocardiography

Authors

1 Cardiology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt

2 Pulmonology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt

Abstract

Background: Obstructive sleep apnea (OSA) is a widespread chronic sleep disorder that greatly increases the risk of both non-fatal and fatal cardiovascular events, as well as overall mortality. Extensive evidence supports this connection. Aim: Evaluate biventricular function, arrhythmias, cardiac autonomic function, and cardiovascular outcomes in OSA patients. Methods: We enrolled 40 OSA patients and 20 healthy controls, using ECG, ambulatory blood pressure monitoring, and echocardiography to assess ventricular function and strains. Results: OSA patients had higher LV volumes, mildly reduced ejection fraction, impaired strain, larger LA volumes, and right ventricular dysfunction. They also showed higher heart rates and elevated blood pressure compared to controls, indicating early biventricular changes. Conclusion: OSA significantly affects cardiac function and dimensions, causing diastolic dysfunction, increased non-dipping, higher minimum heart rate, and elevated daytime, nighttime, and overall ambulatory blood pressure.

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