Short and Long Term Assessment of Renal Function after Maximum Allowable Dose of Iodinated Contrast Media in Middle Aged Patients with Type 2 Diabetes Mellitus after Elective Coronary Intervention

Authors

Cardiovascular Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Abstract

Background: Coronary intervention is one of the most useful tools we use in our daily practice to manage our cases. Diabetes mellitus is a major public health problem worldwide. Aims and objectives: To assess short and chronic changes in the function of the kidney in middle-aged cases between 35 and 55 years old with type 2 diabetes mellitus undergoing elective coronary intervention following a maximum allowable dose of iodinated contrast media (MACD). Patients and methods: This prospective cohort research has been performed on a hundred consecutive diabetic cases between 35 and 55 years old undergoing elective cardiac catheterization in the Cardiology Department at Mansoura University Hospitals and Mahalla Cardiac Center for 6 months from January 2022 to June 2022. Results: Our results show a statistically significant difference between the three measurements regarding serum creatinine and creatinine clearance. Pairwise comparisons revealed a statistically significantly higher serum creatinine and a statistically significantly lower creatinine clearance at 6 months vs. both baseline and 24-hour readings but not between baseline and 24-hour readings. Postoperative twenty-four hours' serum creatinine less than 1.5 mg/dl cases = 77. (68) cases, 88.3% still Conclusion: Long-term kidney function assessment is crucial for detecting changes in serum creatinine and creatinine clearance, which is vital for early detection and treatment.