The Role of Endoscopic Ultrasound in Detection of Liver Metastasis among Patients with Pancreatic Cancer

Authors

1 Gastroenterology and Hepatology Unit, Department of Internal Medicine, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt

2 Diagnostic and Intervention Radiology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt

Abstract

Background: Pancreatic cancer (PC) is one of the deadly types of cancer. More than half of cases present with liver metastasis. Liver metastasis detection is essential to determine the best treatment plan for patients. Recently, Endoscopic Ultrasound (EUS) showed superiority in the detection of PC liver metastasis. Aim: To evaluate the role of EUS in the detection of liver metastasis among patients with pancreatic cancer. Patients and Methods: Patients included (n=63) were subjected to EUS examination. EUS assessment of pancreatic lesions, lymph nodes, vasculature, and liver metastasis was conducted in all included patients. Diagnosis of pancreatic cancer and liver metastasis based on histopathology. Results: A total of 63 patients with PC included their mean age 57.16 ± 12.05 years. 14 (22.2%) patients had liver metastasis on histopathology. All of them detected with EUS and 12 patients detected on computed tomography (CT). Male sex and lower body mass index (BMI) identified as risk factor for liver metastasis. The sensitivity and specificity of EUS in detection of liver metastasis among patient with PC were 100%. Conclusion: Twenty-three percent of patients with pancreatic cancer have liver metastasis, according to our results. EUS has good sensitivity, specificity, and accuracy in the detection of pancreatic cancer liver metastasis.

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