Comparative Study of Different Types of Iron Preparations in Correction of Anemia in Third Trimester by Intravenous Route

Background: Iron Deficiency Anemia (IDA) is the most severe result of iron deficiency and is still regarded as the most frequent dietary deficit globally. Aims and objectives: To assess the safety and efficacy of distinct types of iron preparations in the correction of anemia in the third trimester by intravenous route. Patients and methods: This prospective comparative investigation has been performed on 150 pregnant females in the third trimester of pregnancy diagnosed with iron deficiency anemia who have been selected from attendees of outpatient Obstetrics & Gynecology clinics of El-Hussein Hospitals. The period of this investigation was 10 months. All cases have been randomized by the computer into 3 groups: group A (receive iron maltos/hemojet), group B (receive iron sucrose/ferosac), and group C (receive iron dextran/cosmofer). Results: Comparison of the iron profile showed statistically insignificant variance among the three groups. Follow-up of HB and ferritin one month after treatment in our studied population showed improved HB and ferritin in all three 3 groups with statistically insignificant variance among the three groups regarding ferritin, while there was statistically significant variance higher in group C than group A and B as regard HB. Conclusion: The study found a significant improvement in hemoglobin (HB) and ferritin levels following one month of treatment in all three maltose, sucrose, and iron dextran groups. No significant differences were found in iron, ferritin, TIBC, TS% levels, red blood cells, hematocrit, mean corpuscular volume, white blood cells, and platelet counts.