Early resolution of ST-segment Elevation after Reperfusion Therapy for Acute Myocardial Infarction and It's Relation to Left Ventricular Functions by Echocardiography

Background: Cardiovascular diseases (CVD) are the most common cause of death, accounting for thirty-one percent of all fatalities annually and affecting approximately 17.9 million people annually, in accordance with WHO statistics. Aim: To evaluate the early ST-segment resolution (STR) after acute ST-elevation myocardial infarction (MI) (STEMI) revascularization by percutaneous coronary intervention (PCI) or thrombolytics and its relation to global left ventricle (LV) function echocardiographic- study. Patients and methods: The present prospective research was carried out on 100 cases with STEMI underwent primary (1ry) PCI or thrombolytic therapy. Fifty patients underwent PPCI and 50 patients received fibrinolytic therapy at coronary care unit admitted to Al-Azhar Assuit university hospital and Assuit university hospital. Results: ST resolution after 90 minutes in relation to Echocardiographic (2D) at baseline and after 3 months on PCI group show statistically significant in EF (Ejection Fraction), ESV (End Systolic Volume) with (<50%) ST resolution, and in EDV in (>70%) ST resolution, otherwise no statistical difference found. ST resolution after 90 minutes in the thrombolytic group in relation to Echocardiographic (2D) at baseline and after 3 months show statistically significant in EF in no ST resolution and ESV in (<50%) ST resolution; otherwise, no significant difference was found. Diastolic Function after 3 months demonstrated no substantial static variation among the PCI and thrombolytic therapy groups. Conclusion: Early ST-segment resolution after reperfusion of STEMI, either by PPCI or Thrombolytic therapy, is associated with a better effect on EF (Ejection fraction) and EDV (End diastolic Volume).