Impact of Neutrophil to lymphocyte ratio as a predictive marker for mortality in Medical Intensive Care septic patients

Authors

1 Internal Medicine, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt

2 Clinical Pathology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt

Abstract

Background: An uncontrolled host reaction to an infection can result in organ failure and sepsis, a potentially fatal illness. Severe organ dysfunction brought on by infection is a clinical illness known as sepsis. When it comes to severe sepsis, mortality rates can range from 25% to 30%, whereas septic shock can have mortality rates of 40% to 70%. Aim and objectives: To evaluate the usefulness of NLR as a mortality predictive factor in septic patients receiving medical intensive care unit(MICU) treatment. Patients and methods: In this prospective trial, 150 consecutive adult patients with sepsis-63 females with a mean age of 49.5 years and 87 males with a mean age of 52.5 years divided into two groups: survivors(n=122) and non-survivors(n=28) at MICU, Department. Results: With a cutoff value of >10.6, NLR exhibited a considerable amount of predictive power for mortality among septic patients, exhibiting 88.3% sensitivity and 94.6% specificity. Conclusion: In cases of sepsis, NLR may be a helpful predictive and diagnostic sign. When comparing the NLR distributions of the two groups under study, the survivors group and the non-survivors the non-survivors group had higher NLR values and were substantially more frequent than the survivors group.

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