Using vaginal progesterone in Treatment of women with Threatened miscarriage and low serum progesterone level

Background; The most frequent gynaecological emergency is threatened miscarriage, which is characterised by vaginal bleeding with or without abdominal pain in the early stages of pregnancy. 15-20% of pregnancies are affected by this disorder, and 20-25% of those finally end in spontaneous miscarriage. Investigation of the effects of vaginal progesterone use in TTT of women who are at risk of miscarriage and have low serum progesterone levels are the goal and objectives., Subjects and methods; On the campus of Al-Azhar University's Al-Hussein Hospitals, this experimental study was carried out.100 pregnant participants who were at risk for miscarriage were split into two groups based on their serum progesterone levels for this study. The duration of the study ranged from 6-12 months, Result; The progesterone level in Group 1 ranged from 34.51 to 41.83 with a mean and standard deviation of 37.82 1.74, while in Group 2 Subgroup A the progesterone level ranged from 11.62 to 34.98 with a mean and standard deviation of 22.11 6.44 and in Group 2 Subgroup B the progesterone level ranged from 10.92 to 37.16 with a mean and standard deviation of 23.18 6.42, with a Between the three groups under study, miscarriage was significantly different (p=0.015).RDS showed a significant difference between the three study groups (p=0.014). Conclusion; Vaginal progesterone is helpful in reducing the risk of miscarriage in women who have low serum progesterone levels and are at risk of miscarriage,,