Role of Serum Amyloid A Levels in Preeclampsia

Background: Preeclampsia (PE)is a frequent pregnancy complication and a leading factor in mother and fetal death. The maternal plasma level of SAA may be anticipated to be higher compared to levels seen during a typical pregnancy since preeclampsia is linked to extensive endothelial malfunction, which is thought to be triggered by an enhanced maternal systemic inflammatory response. The maternal plasma level of SAA during a healthy pregnancy may vary from that during a non-pregnancy owing to changes in the inflammatory response, elevated hormone balance, and/or increased adipose tissue. Patients and Methods: At the Department of Obstetrics and Gynecology, Al-Hussein and Sayed Galal Hospitals, Al-Ahar University, and El Dalangat general hospital, 100 women were separated into two groups for this prospective case-control research: (Group I): (Cases group): included50 pregnant preeclamptic women, (Group II): (Control group): included50 pregnant non-preeclamptic women who matched in age, and gestational age with the case group between December 2019 to December 2020. Results: Regarding Serum Amyloid A, there were statistically substantial variations between groups where P Conclusion: Serum amyloid A is a promising biomarker in detect ability and predictability of the pathological development of preeclampsia. Future research studies should be conducted in a multicentric fashion.