Evaluation of Non-Compressive Myelopathy in a Sample of Egyptian Patients

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Department of Neurology, Faculty of Medicine for boys, Al-Azhar University, Cairo, Egypt.

Abstract

Background; "Spinal cord malfunction in the lack of clinico-radiological evidence of spinal cord compression" is the definition of non-compressive myelopathy. In the absence of imaging modalities that show compression, it may be caused by demyelinating, viral, autoimmune, vascular, degenerative, and metabolic illnesses. Aim and objectives: The goal of this research was to assess the etiological factors of non-compressive myelopathy in a sample of Egyptian patients. Subjects and methods: Between January 1 and June 30, 2022, researchers at Cairo, Egypt's Al-Azhar University Hospitals (Al-Hussein and Sayed Galal) performed a prospective observational study on patients with non-compressive myelopathy. At three and six months, patients were followed up on to assess any lingering impairments and disabilities. Results: The study had 60 patients with median age of 30.70 ±12.4 years where female: male ratio was 1.3:1. Diagnostic classification/NCM was MS spectrum in 32(53.3%) patients, Idiopathic ATM in 10(16.7%), NMO spectrum in 6(10.0%), HSP in 8(13.3%), Infections/Para infection (Viral myelitis) in 2(3.3%), and ADEM in 2(3.3%). Conclusion: According to the finding in the present study, a wide range of diseases present with non-compressive myelopathies. In the majority of cases, the definitive diagnosis can be reached with a thorough history and clinical examination along with the proper workup. Our diagnostic precision has improved because of neuroradiology and serological indicators. Immediate diagnosis of these diseases makes them reversible, therefore, a proper treatment can improve the outcomes of this disease.

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